David Duchovny

Fox Mulder

Gillian Anderson

Dana Scully

Annabeth Gish

Monica Reyes

Mitch Pileggi

Walter Skinner

William B. Davis

Cigarette Smoking Man

Lauren Ambrose

Agent Einstein

Robbie Amell

Agent Miller

Barbara Hershey

Erika Price

Anjali Jay

Dr. Joyet

Sandrine Holt

Dr. Karah Hamby

A.C. Peterson

Mr. Y

Dejan Loyola

Agent Colquitt

Karin Konoval

Little Judy Poundstone / Little Chucky Poundstone

Denise Dowse

Dr. Babsi Russel

Alison Araya

Nurse Vickie Easton

Lossen Chambers

Nurse Peggy Easton

Brian Huskey

Reggie Something

Bill Dow

Pangborn

Stuart Margolin

Dr. Thaddeus Q. They

Dan Zukovic

Martin

Alex Diakun

Buddy / Devil

Louis Ferreira

Detective Costa

François Chau

Peter Wong

Cameron Forbes

Dr. Harris

Sunita Prasad

Dr. Aliyeh Scholz

Devon Alexander

Barista

Cory Rempel

Young Walter Skinner

Brendan Patrick Connor

Sheriff Mac Stenzler

Patrick Keating

Beggar

Peter Hall

Dr. Matthew Wegweiser

Robert Mann

Hillbilly Ed

Shane Symons

Other Marine

Johnson Phan

Quon

Candus Churchill

Shirley

Ashley Lambert

Bigly Customer Service (voice)

Matt Corboy

Voice of Science (voice)

Sitara Attaie

E-Norm-Uz Customer Service (voice)

Kristen Cloke

Wendy (voice)

Alex Carter

Chief Strong

Jason Gray-Stanford

Officer Eggers

Erin Chambers

Anna Strong

Sharon Taylor

Diana Eggers

Roger Cross

Officer Wentworth

Sebastian Billingsley-Rodriguez

Andrew Eggers

Michael Q. Adams

Pastor

Emma Oliver

Emily Strong

Sean Campbell

Officer Sean

Ken Godmere

Melvin Peter

Keith Arbuthnot

Mr. Chuckleteeth

Kwesi Ameyaw

Judge

Fiona Vroom

Barbara Beaumont / Sitcom Barbara

Carlena Britch

Juliet 'La Avispa' Bocanegra

Jere Burns

Dr. Randolph Luvenis

Viv Leacock

Price

Samuel Patrick Chu

Warren

Fabiola Colmenero

Josephine Bocanegra

Genevieve Buechner

Kayla

Albert Nicholas

Agent Bill Bludworth

Aidan Kahn

Agent Colquitt

Jay Hindle

Sitcom Joe

Miles Robbins

Jackson Van De Kamp / William

Andre Roshkov

Commander Al

James Pickens Jr.

Alvin Kersh

West Duchovny

Maddy

Zak Santiago

Mr. Green

Ben Cotton

Mr. Paulsen

Sarah Jeffery

Brianna Stapleton

Madeleine Arthur

Sarah Turner

Joel McHale

Tad O'Malley

Jeremy Jones

Sergeant

Thabo Ketshabetswe

Guard

Jett Klyne

Young Spender

Donald Trump

Self (archive footage) (uncredited)

Michael Flynn

Self (archive footage) (uncredited)

Haley Joel Osment

Young John 'Kitten' James / Davey James

Chris Owens

Jeffrey Spender

Dean Haglund

Richard 'Ringo' Langly